Although silicones were presumed to be inert materials, immune-mediated reactions in human and animal tissues have been reported since the beginning of the use of silicone implants (1–5). Silicone has been implicated as the causative agent of chronic local or systemic reactions such as inflammatory processes, foreign-body reactions or rheumatologic diseases. However, at present, only one case of immediate-type hypersensitivity to silicone has been reported (5). We report a case of immediate pruritus, oedema and erythema upon the first insertion of a silicone nasogastric tube in a 10-year-old boy.
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