Our Stolen Future: Non-monotonic dose-response curves
The "dose makes the poison" is a common adage in toxicology. It implies that larger doses have greater effects than smaller doses. That makes common sense and it is the core assumption underpinning all regulatory testing. When "the dose makes the poison," toxicologists can safely assume that high dose tests will reveal health problems that low dose exposures might cause. High dose tests are desirable because, the logic goes, they not only will reveal low dose effects, they will do so faster and with greater reliability. Greater reliability and speed also mean less cost. learn more;
